Celebrex vs Mobic – A Look at Their Differences

Celebrex is the trade name for a prescription drug, celecoxib, while Mobic is the brand name for meloxicam. Both of these drugs are categorized as non-steroidal anti-inflammatory drugs but both of them have their own differences. The efficacy of one drug may differ from the other based on the response of the patient and the presence of underlying conditions.

Celebrex vs Mobic: On Their Function

Prostaglandin is a hormone-like substance that activates inflammatory response and produce pain. Both Celebrex and Mobic act as pain relievers by inhibiting prostaglandin production; however, it is shown that Celebrex or celecoxib has the ability to slow down the proliferation of tumor cells in the colon.

Celebrex vs Mobic: On Their Therapeutic Use

Doctors may prescribe either Mobic or Celebrex as treatment of pain and inflammation associated with arthritis. Moreover, Celebrex can be effective as a pain reliever for ankylosing spondylitis and for severe menstrual cramps, as well as preventing the reoccurrence of intestinal polyps.

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Special Features of Both Drugs

Food can have an effect on the efficacy of some drugs; some drugs require food to exhibit their efficacy better, while some are most effective when taken without meals. For meloxicam, food has no effect on its efficacy, but for Celebrex, it is more effective when it is taken with food, particularly for doses that exceed 200mg.

Convenience of Dosing

Two doses of celecoxib a day may sometimes be necessary to treat arthritis more effectively. As for meloxicam, it is usually prescribed as one dose per day. Dosing is important since it can influence a patient’s compliance to the treatment regime. Patients may prefer to take the drug which can provide relief at the minimum amount of dosing.

Comparison on Their Side Effects

Celecoxib is a selective COX-2 inhibitor, while meloxicam is a preferential COX-2 inhibitor, which means that Mobic is just as effective as other NSAIDs but without the gastrointestinal upsets produced by NSAIDs like ibuprofen or naproxen, or the increased risk of heart attack from COX-2 inhibitors like celecoxib.
Special considerations for Both Drugs

Some people have allergic reactions to sulfa-based drugs. In our comparison of Mobic and Celecoxib, the latter has a sulfa compound which means that it is not safe for use in patients who have a sulfonamide or sulfa allergy, as well as a history of hepatitis. For those who have this kind of allergy, an alternative is Mobic and may be well tolerated.


In the comparison between Celebrex vs Mobic, one can be more superior than the other; it all depends on the patient’s response to the treatment. Some patients may respond well to celecoxib and not to meloxicam, and vice versa. Your doctor will be able to tell you which of the two can provide you with maximum pain relief with minimal side effects.

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